Lek Bensedin, rastvor za injekciju/infuziju se koristi za smanjenje anksioznosti i postizanje sedacije kod teške akutne anksioznosti ili agitacije, kao i za terapiju agitacije povezane sa delirium tremens.
Takođe je prijavljena i salivarna hipersekrecija. Potreban je oprez pri započinjanju terapije klozapinom kod pacijenata koji već uzimaju diazepam. Postoji povećan rizik od hipotenzije, bradikardije i respiratorne depresije prilikom parenteralne primene benzodiazepina i intramuskularne primene olanzapina.
Kod pacijenata sa hroničnim oboljenjem jetre neophodno je smanjiti dozu diazepama. Neophodan je medicinski nadzor kada se pacijentima sa oštećenom funkcijom jetre primenjuje lek Bensedin rastvor za injekciju/infuziju u dozi od 0,625 mg/kg/dan ili većoj (ekvivalentno dozi od 50 mg/kg/dan propilenglikola).
Istovremena primena sa rifampicinom značajno smanjuje koncentraciju diazepama, što smanjuje njegovo dejstvo. Potrebno je izbegavati istovremenu primenu rifampicina i diazepama.
Opioids might cause dependancy and you may get withdrawal indications if you quit taking it quickly. Your prescriber should have defined just how long you're going to be taking it for and when it is suitable to prevent, how to do this properly.
Primena leka Bensedin, rastvor za injekciju/infuziju u ovoj populaciji mora se procenjivati od slučaja do slučaja (videti odeljak „Doziranje i način primene”).
Never abruptly prevent having this medicine. In order to end getting this medication, talk about this with all your prescriber to start with. They will inform you how To accomplish this, usually by cutting down the dose little by little in order that any uncomfortable withdrawal effects are saved to a minimum amount.
The quantity of paracetamol in the 4 distinct strengths is the same (500 mg), but the quantity of dihydrocodeine differs and this decides the energy on the preparation.
Antivirusni lekovi inhibiraju CYP3A4 metabolički place diazepama. Povećan je rizik od bensedin effects sedacije i respiratorne depresije. Zbog toga treba izbegavati istovremenu primenu.
Itrakonazol, ketokonazol i u manjoj meri flukonazol i vorikonazol su snažni inhibitori izoenzima CYP3A4 citohroma P450 i mogu povećati koncentraciju benzodiazepina u plazmi.
Treba imati na umu aditivni efekat leka Bensedin, rastvor za injekciju/infuziju sa drugim lekovima koji sadrže propilenglikol i/ili bilo koji supstrat alkohol dehidrogenaze i/ili dijetetskim unosom ovih ekscipijenasa.
Remember to inform your physician about all sedative medicines you might be having and follow your physician’s dose advice closely. It could be practical to inform close friends or family members to concentrate on the indicators and signs stated previously mentioned. Call your medical professional when dealing with these types of symptoms.
A “spiked” consume, that means one which has a drug added to it with no your know-how, is usually a threat to any one, irrespective of sexual intercourse or gender. It’s also vital that you do not forget that you may not have the capacity to style a big difference inside a spiked consume.
They’re A great deal safer than their predecessors. In advance of benzodiazepines, Medical doctors mostly check here prescribed barbiturates for treating stress and anxiety. But these medication arrived with major risks of aspect effects and problems.